Definition
Slow intravenous administration of ketamine over 40-60 minutes, typically dosed at 0.5 mg/kg, used off-label for treatment-resistant depression. The most-studied ketamine-administration route in psychiatric research.
Related Terms
Ketamine
A dissociative anesthetic developed in the 1960s, now used at sub-anesthetic doses for treatment-resistant depression and other mental health conditions.
Ketamine-Assisted Therapy
A clinical protocol in which sub-anesthetic doses of ketamine are administered (IV, IM, oral, or intranasal) under medical supervision to treat depression, PTSD, anxiety, or chronic pain — typically combined with structured psychotherapy.
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